Terms & Conditions

CPN Challenge, Stage I, Round 2 Terms & Conditions

*These terms and conditions were updated to align with the opening of the second round of Stage I applications on October 7, 2015.

 

Terms used:

The Organizers – Conquer Paralysis Now™ (CPN), and any people acting on their behalf, are hereby collectively referred to as the “Organizers”.


Challenge Program – the set of awards announced under the CPN Challenge.


Award – a prize or grant under the CPN Challenge Program. A prize or grant offered in a subsequent year, but with the same title, is considered a separate award.


Scientific Awards – this term encompasses the following awards: Translation; Cross-over; Collaboration; New Investigator; Out of the Box; Reaching and Grasping.


SAC – the Scientific Advisory Council, the panel that makes the final recommendation on winners of the scientific awards.


Online Judges – judges that provide an initial evaluation of applications, which is completed online via the InnoCentive Custom Challenge portal. 


Judges – comprises the SAC and online judges.


Applicant – The entity that has submitted an application for an award(s) in the CPN Challenge Program.


Winner – the recipient of an award.


SCI – the abbreviation used to refer to spinal cord injury.



               1.1    Eligibility of entry

1. Any work involving human subjects must obtain informed consent of the subject or legal guardian(s) and provide information about potential risks, and they must provide for the safeguard of human rights and welfare at a standard equivalent to that prescribed by the U.S. Department of Health and Human Services and the Federal Drug Administration (or the equivalent institution in the country where the study is performed). Satisfactory evidence indicating approval of the protocols and procedures by appropriate ethical review boards must be submitted before any money will be disbursed and the Organizers reserve the right to require that the standards prescribed by the U.S. Food and Drug Administration be substituted for local standards after any submission.

2. Employees of the Organizers of the CPN Challenge Program and their families (including, but not limited to, aunts, uncles, cousins, grandparents, etc.). are not permitted to enter.


3. Only one entry per person or business per award is permitted. Repeat applications from multiple accounts shall be disregarded.


4. Applicants must be at least 18 years of age or must not be classified as a minor in their country of residence.


5. This CPN Challenge Program and/or the entry into this Challenge is void where prohibited. All other applicable laws and regulations apply.


6. The Laws of the state of Missouri, U.S.A., govern the CPN Challenge Program and any controversy shall be managed and resolved through the laws of the state of Missouri.  


7. Applicants must agree that the information in their application will be accurate and will not, to the best of their knowledge: (a) infringe any third party’s copyright, trademark, patent or other proprietary rights or rights of publicity or privacy, (b) violate any law (including without limitation those governing export control, consumer protection, unfair competition, anti-discrimination or false advertising), or (c) be libelous, unlawfully threatening, or unlawfully harassing. Applicants may be asked to make legally binding warranties and representations to the Organizers in relation to a proposed work that they submit.


8. In case of debate around eligibility, the Organizers have sole discretion to decide whether the application is eligible.



               1.1.1  Cross -over Award

 

9. Applications for research grants are accepted from international investigators located at institutions that have clearly established lines of accountability and fiscal responsibility.


10. Applications must include institutional assurances regarding their license to perform research on human subjects and/or on animals (where relevant), signed by the individual responsible for administration of the contract.


11. Applicants must attach letters of support from their advisors and collaborators. These letters must include a clear statement that the applicant is allowed to use lab resources and will receive mentorship from his/her supervisor.


12. All proposals must be suitable for chronic SCI models. If acute models are used, the grant application must clearly state how and why the additional effort of using a chronic model is not justified and how the idea would be translated to a chronic model.


13. No part of these grants can be used for indirect costs nor for the salaries of laboratory staff who will not be executing the work –. Grant funding should only be allocated to the people executing the actual work proposed in the awarded application.


14. Submissions are judged according to the following 
judging criteria:

 

Criteria

Description

Weighting

Novelty

Does the research bring new knowledge or a novel approach to SCI research?

2

 

Feasibility of crossover

Is there convincing rationale and evidence for why this idea could potentially crossover effectively from the existing context into SCI research?

2

Relevance to the mission of the Conquer Paralysis Program.

Would the proposed work advance SCI research towards the goal of the Conquer Paralysis Program (recovery of key functions)?

2

Design of proposed project

Is the proposed project suitably designed to address the hypothesis?

2

Impact on future research

To what extent would the study inform future SCI research (even if the results were negative)?

1

Detail of budget

Is the budget clearly outlined and costs clearly defined for different elements of research (e.g. salary split, supplies, travel, animals etc.)?

1

Risk Analysis

Are the risks understood and clearly outlined in the proposed study?

1

Quality of the applicant (or team)

Does the applicant have the scientific expertise to conduct the proposed research?

2

Potential for future clinical application

Does the proposed work have the potential for functional recovery in chronic SCI human subjects?

2

Steps to Human Translation

Are the future steps for continued translation outlined effectively so that a certificate to start human trials is achievable?

1

 

1.1.2  Translation Award

 

15. Only applications which propose research deemed by the Organizers to be in the spinal cord injury field will be accepted.


16. Applications for research grants are accepted from international investigators located at institutions that have clearly established lines of accountability and fiscal responsibility.

17. Applications must include institutional assurances regarding their license to perform research on human subjects and/or on animals (where relevant), signed by the individual responsible for administration of the contract.

18. Applicants must attach letters of support from their advisors and collaborators. These letters must include a clear statement that the applicant is allowed to use lab resources and will receive mentorship from his/her supervisor.

19. All proposals must be suitable for chronic SCI models. If acute models are used, the grant application must clearly state how and why the additional effort of using a chronic model is not justified and how the idea would be translated to a chronic model.

20. No part of these grants can be used for indirect costs nor for the salaries of laboratory staff who will not be executing the work. Grant funding should only be allocated to the people executing the actual work proposed in the awarded application.

 


21. Submissions are judged according to the following 
judging criteria:

 

Criteria

Description

Weighting

Feasibility

To what extent does the application strike a balance between being feasible, while at the same time being too unpredictable in its success to obtain funding from other sources such as National Institutes of Health (NIH), National Science Foundation (NSF), or local equivalents?

2

 

Potential value of translational research

Could this project help generate results that will lead to further funding of this approach, in order for the translational research to continue further?

2

Relevance to the mission of the Conquer Paralysis Program.

Would the proposed work advance SCI research towards the goal of the Conquer Paralysis Program (functional recovery of SCI patients)?

2

Design of proposed study/project

Is the proposed project suitably designed to address the hypothesis?

2

Impact on future research

To what extent would the study inform future SCI research (even if the results were negative)?

1

Detail of budget

Is the budget clearly outlined and costs clearly defined for different elements of research (e.g. salary split, supplies, travel, animals etc.)?

1

Risk Analysis

Are the risks understood and clearly outlined in the proposed study?

1

Quality of the applicant (or team)

Does the applicant have the scientific expertise to conduct the proposed research?

2

Potential for future clinical application

Does the proposed work have the potential for functional recovery in chronic SCI human subjects?

2

Steps to Human Translation

Are the future steps for continued translation achievable and outlined effectively so that they would lead to a certificate to start human trials?

1

 

1.1.3  New Investigator Award

22. The following conditions must both be met for applications to be deemed eligible:

§  As of October 7, 2015, the applicant must have entered the field of SCI research in the last 2 years.

§  As of October 7, 2015, the applicant must have graduated from their PhD more than 1 year ago.

 

23. Applications for research grants are accepted from international investigators located at institutions that have clearly established lines of accountability and fiscal responsibility.


24. Applications must include institutional assurances regarding their license to perform research on human subjects and/or on animals (where relevant), signed by the individual responsible for administration of the contract.


25. Applicants must attach letters of support from their advisors. These letters must include a clear statement that the applicant is allowed to use lab resources and will receive mentorship from his/her supervisor.


26. All proposals must be suitable for chronic SCI models. If acute models are used, the grant application must clearly state how and why the additional effort of using a chronic model is not justified and how the idea would be translated to a chronic model.


27. No part of these grants can be used for indirect costs nor for the salaries of laboratory staff who will not be executing the work . Grant funding should only be allocated to the people executing the actual work proposed. in the awarded application


28. Submissions are judged according to the following 
judging criteria:

 

Criteria

Description

Weighting

Novelty

Does the investigator bring new knowledge or a novel approach to SCI research?

2

Relevance the mission of the Conquer Paralysis Program.

Would the proposed work advance SCI research towards the goal of the Conquer Paralysis Program (functional recovery for SCI patients)?

2

Relevance to the SCI field

If the application is from another field, is the rationale for why it could be applied to SCI clear and convincing?

1

Design of proposed project

Is the proposed project suitably designed to address the hypothesis?

2

Impact on future research

To what extent would the study inform future SCI research (even if the results were negative)?

1

Detail of budget

Is the budget clearly outlined and costs clearly defined for different elements of research (e.g. salary split, supplies, travel, animals etc.)?

1

Risk Analysis

Are the risks understood and clearly outlined in the proposed study?

1

Quality of the applicant (or team)

Does the applicant have the scientific expertise to conduct the proposed research?

2

Potential for future contributions to the field

Does the researcher have the potential to make valuable contributions to functional recovery in chronic SCI human subjects?

4

 

1.1.4   Collaboration Award

29. The consortium of members in the application must: 

     i. Be interdisciplinary

     ii. Be from at least two different labs that focus on different fields of study

     iii. Have not previously collaborated on a project

     iv. Have at least one person from each lab working on the project

30. Applications for research grants are accepted from international investigators located at institutions that have clearly established lines of accountability and fiscal responsibility.

31. Applications must include institutional assurances regarding their license to perform research on human subjects and/or on animals (where relevant), signed by the individual responsible for administration of the contract.


32. Applicants must attach letters of support from their advisors and collaborators. These letters must include a clear statement that the applicant is allowed to use lab resources and will receive mentorship from his/her supervisor.


33. All proposals must be suitable for chronic SCI models. If acute models are used, the grant application must clearly state how and why the additional effort of using a chronic model is not justified and how the idea would be translated to a chronic model.

34. No part of these grants can be used for indirect costs nor for the salaries of laboratory staff who will not be executing the work . Grant funding should only be allocated to the people executing the actual work proposed. in the awarded application

35.  Submissions are judged according to the following judging criteria:

Criteria

Description

Weighting

Novelty

Does this collaboration bring new knowledge or a novel approach to SCI research?

1

Collaborative and interdisciplinary approach

How likely is it the collaboration will produce innovation due to the complementing structure of its partners and the way the collaboration will be implemented (e.g. emails vs. joint and shared workspaces)?

2

Relevance to the mission of the Conquer Paralysis Program.

Would the proposed work advance SCI research towards the goal of the Conquer Paralysis Program (functional recovery for SCI patients)?

2

Relevance to the SCI field

If the application is from another field, is the rationale for why it could be applied to SCI clear and convincing?

1

Design of proposed project

Is the proposed project suitably designed to address the hypothesis?

2

Impact on future research

To what extent would the study inform future SCI research (even if the results were negative)?

1

Detail of budget

Is the budget clearly outlined and costs clearly defined for different elements of research (e.g. salary split, supplies, travel, animals etc.)?

1

Risk Analysis

Are the risks understood and clearly outlined in the proposed study?

1

Quality of the applicant (or team)

Does the applicant have the scientific expertise to conduct the proposed research?

2

Potential for future clinical application

Does the proposed work have the potential for functional recovery in chronic SCI human subjects?

2

Steps to Human Translation

Are the future steps for continued translation achievable and outlined effectively that would lead to a certificate to start human trials?

1

1.1.5    Out of the Box Award

36. All submissions in adjacent fields such as stroke, traumatic brain injury, Amyotrophic lateral sclerosis, Parkinson’s disease and multiple sclerosis will be accepted, so long as:

     i. All submissions in fields adjacent to SCI clearly and concisely argue why the proposed research is important for the field of chronic SCI and elaborate on strategies and steps necessary to translate the results (if successful).

     ii. All research in stroke/TBI can only concern chronic injury models. 

     iii. Applications from adjacent fields that can also have an impact on SCI will be ranked higher if the proposal clearly outlines how even negative results would inform future SCI research.
37. Applications for research grants are accepted from international investigators located at institutions that have clearly established lines of accountability and fiscal responsibility.


38. Applications must include institutional assurances regarding their license to perform research on human subjects and/or on animals (where relevant), signed by the individual responsible for administration of the contract.


39. Applicants must attach letters of support from their advisors and collaborators. These letters must include a clear statement that the applicant is allowed to use lab resources and will receive mentorship from his/her supervisor.


40. All proposals must be suitable for chronic SCI models. If acute models are used, the grant application must clearly state how and why the additional effort of using a chronic model is not justified and how the idea would be translated to a chronic model.


41. No part of these grants can be used for indirect costs nor for the salaries of laboratory staff who will not be executing the work . Grant funding should only be allocated to the people executing the actual work proposed. in the awarded application


42. Submissions are judged according to the following 
judging criteria:

 

Criteria

Description

Weighting

Novel and disruptive concept

To what extent does the application contain high risk, high potential work, which has the potential to take a truly novel and ‘out of the box’ approach to SCI research?

3

Relevance to the SCI field

If the application is from another field, is the rationale for why it could be applied to SCI clear and convincing?

1

Relevance to the mission of the Conquer Paralysis Program.

Would the proposed work advance SCI research towards the goal of the Conquer Paralysis Program (recovery of key functions)?

 

2

Design of proposed study

Is the proposed study suitably designed to address the hypothesis?

2

Impact on future research

To what extent would the study inform future SCI research (even if the results were negative)?

1

Detail of budget

Is the budget clearly outlined and costs clearly defined for different elements of research (e.g. salary split, supplies, travel, animals etc.)?

1

Risk Analysis

Are the risks understood and clearly outlined in the proposed study?

1

Quality of the applicant (or team)

Does the Solver have the scientific expertise to conduct the proposed research?

2

Potential for future clinical application

Does the proposed work have the potential for functional recovery in chronic SCI human subjects?

2

Steps to Human Translation

Are the steps for translation to humans achievable and outlined effectively?

1

 

1.1.6  Reaching and Grasping award

43. All submissions in adjacent fields such as stroke, traumatic brain injury, Amyotrophic lateral sclerosis, Parkinson’s disease and multiple sclerosis will be accepted, so long as:

     i. All submissions in fields adjacent to SCI clearly and concisely argue why the proposed research is important for the field of chronic SCI and elaborate on strategies and steps necessary to translate the results (if successful).

     ii. All research in stroke/TBI can only concern chronic injury models. 

     iii. Applications from adjacent fields that can also have an impact on SCI will be ranked higher if the proposal clearly outlines how even negative results would inform future SCI research

44. Applications for research grants are accepted from international investigators located at institutions that have clearly established lines of accountability and fiscal responsibility.

45. Applications must include institutional assurances regarding their license to perform research on human subjects and/or on animals (where relevant), signed by the individual responsible for administration of the contract.


46. Applicants must attach letters of support from their advisors and collaborators. These letters must include a clear statement that the applicant is allowed to use lab resources and will receive mentorship from his/her supervisor.


47. All proposals must be suitable for chronic SCI models. If acute models are used, the grant application must clearly state how and why the additional effort of using chronic models is not justified and how the idea would be translated to a chronic model.


48. No part of these grants can be used for indirect costs nor for the salaries of laboratory staff who will not be executing the work . Grant funding should only be allocated to the people executing the actual work proposed. in the awarded application


49. Submissions are judged according to the following 
judging criteria:



Criteria

Description

Weighting

Relevance to the Stage III arm/hand function area

Would the proposed work advance SCI research towards the goal of restoring arm/hand function?

3

Novelty

Does the application bring new knowledge or a novel approach to SCI research?

2

Relevance to the SCI field

If the application is from another field, is the rationale for why it could be applied to SCI clear and convincing?

1

Design of proposed study

Is the proposed study suitably designed to address the hypothesis?

2

Impact on future research

To what extent would the study inform future SCI research (even if the results were negative)?

1

Detail of budget

Is the budget clearly outlined and costs clearly defined for different elements of research (e.g. salary split, supplies, travel, animals etc.)?

1

Risk Analysis

Are the risks understood and clearly outlined in the proposed study?

1

Quality of the applicant (or team)

Does the Solver have the scientific expertise to conduct the proposed research?

2

Potential for future clinical application

Does the proposed work have the potential for functional recovery in chronic SCI human subjects?

2

Steps to human translation

Are the steps for translation to humans achievable and outlined effectively?

1

 



1.2    Participation in the CPN Challenge Program

Prior to full acceptance of an award, prospective winners will be required to sign a grant agreement and/or further documents as required by Conquer Paralysis Now™.  To the extent that these terms and conditions conflict with the grant agreement, the grant agreement will control.


Organizers will not be liable for any damage, loss or disappointment suffered by any person taking part or not being able to take part in the CPN Challenge Program.


Organizers will not be liable for any expenses incurred on behalf of Applicants or those who wish to enter into the CPN Challenge Program including but not limited to online access, telecommunication charges, etc.


By applying to the CPN Challenge Program, applicants consent to have details of their application – other than commercially sensitive information – featured in any media or promotional activity for the CPN Challenge Program being carried out by the Organizers. The Organizers may invite applicants to take part in promotional activities at the Organizers’ expense. The Organizers will contact Applicants in advance of any media request for interviews.


The winners in the CPN Challenge Program will be responsible for any and all taxes or fees associated with the award.


Award winners may be invited to answer questions and speak about their project, if selected, during annual presentation events.

 

1.3    General Award Rules

Communications with Applicants will be by email, to the address provided by said Applicant in the application. The Organizers are not responsible for the reliability, or otherwise, of email, and no corruption of, defect in, or failure or delay in the delivery of, any email communication from the Organizers will entitle an Applicant to an extension of any deadline or timeframe or otherwise entitle an Applicant to make any form of claim.


The relevant judging panel shall recommend the winner from all eligible applications according to the terms and conditions and judging criteria of each award.


Unless otherwise agreed by the applicable parties, the award will be paid to the associated organization of the Applicant.


12 grants of at least $50,000 will be awarded across the 6 Awards. .


Grant money awarded by Conquer Paralysis Now™ is to be used only for the purposes described in the grant application. The study must begin within 6 months of the award letter date or the award will be withdrawn. Furthermore, the research outlined in the application must be completed within a year of the award letter date.


Grant money is to be used only during the period indicated in the grant agreement. Any deviation from this schedule must have prior approval from the Organizers. All unexpended money must be returned to the Organizers within 90 days following conclusion of the grant.


Money follows ideas: if the winner is moving to another non-profit research setting, the award can be transferred (at the discretion of the university). If the winner does not continue the work proposed in their application, unused funds must be returned within sixty (60) days. Transfer of the funds to another principal investigator is not permitted. The Organizers reserve the right to decide whether the transfer of the award is granted.


Conquer Paralysis Now™ will retain 10% of the total grant amount until the final reports are received (see below for details). Payments are subject to compliance with these conditions of grant and satisfactory project performance.


Each project investigators must publish their findings obtained with this grant.


An edited version (edits agreed by Conquer Paralysis Now™ and grantee) of the final report, to be presented as a ‘lessons learned’ document, will be made available to be shared publicly following completion of the project, and will automatically be entered into our Trial & Error prize.


Conquer Paralysis Now must be recognized in any publication that results from the grant. The authors must acknowledge the support of Conquer Paralysis Now™ with the following text: “This work was (in part) supported by a grant from the CPN Challenge, a program of Conquer Paralysis Now™, a Global Project of the Sam Schmidt Foundation.”


Note that any major deviation from the proposed schedule must have the approval of Conquer Paralysis Now™, where ‘major deviation’ is defined as:

•A change which will affect the overall timeline of the project by greater than 10% of the initial proposed timeline

•Any considerable deviation from the proposed topic.

 

1.3.1   Reporting

Each funded project in the Cross-Over award must submit a 2 page results document at the close of each project. This will be reviewed by the Conquer Paralysis Now™ Scientific Advisory Council. This final report must contain: 

 

     i. A summary of 10-15 lines which summarizes the results achieved and their importance and significance for further research

     ii. A 2 page document that describes

          a) An overview of the results that were achieved during the funding period (positive and negative)

          b) Unexpected difficulties experienced during the work and how the researcher reacted to them

          c) Any deviations from the original plan, how they affected the work

          d) A plan how the work is expected to be continued

     iii.A list of publications, patents, talks etc. that resulted (fully or partially) from the funding

1.4    Finality of decision

The decision of the SAC is final and binding on all Applicants and no correspondence shall be entered into. No responsibility is accepted for inaccurate award details supplied by parties other than the Organizers.

 

To ensure the quality and fairness of the CPN Challenge Program, Applicants may be required to back-up their claims to all criteria specified under each award’s description.

 

1.5    Confidentiality and intellectual property

The CPN Challenge Program is designed to provide Applicants with an opportunity to present their ideas and innovations. Intellectual property will not be transferred by reason of entry to the CPN Challenge Program and shall remain with its owner. Judges of the scientific awards will be required to sign a non-disclosure agreement.

Applicants agree to keep confidential any business information about the Organizers, which was obtained from their involvement in the CPN Challenge Program.

 

1.6    Changes to terms and conditions and awards

The Organizers reserve the right to amend these terms and conditions, change the awards on offer, or revise the timeframes for or cancel the CPN Challenge Program, at any time. Applicants will be notified of any such changes by email to the address of which they have notified the Organizers, but will be bound by the changes from the time that they take effect, whether or not such notification is actually received.

Participating in the CPN Challenge Program implies acceptance of the terms and conditions as stated herein.

In any instances where circumstances are not covered by these terms and conditions, the Organizers reserve the right to make the final decision. 

 

 1.7   

In publications relating to the Research which is the subject of this Agreement, the applicants agree that if selected, any research findings and publications shall include a statement that indicates as follows:   “The Research was funded by Conquer Paralysis Now, a 501 ( c ) (3 ) nonprofit organization with a mission to cure paralysis. Conquer Paralysis Now was founded by Sam Schmidt, a former IndyCar driver and now a successful team owner after he sustained a serious spinal cord injury while practicing for the 2000 IndyCar season. Conquer Paralysis Now is leading the charge for a cure through funding scientific research, medical treatment and technological advances benefiting those paralyzed by spinal cord injuries, stroke, diseases such as ALS, Alzheimer’s and Parkinson’s or in other ways. For more information, please visit www.conquerparalysisnow.org

 

 1.8   

This Agreement constitutes the entire understanding and agreement of the parties with respect to the subject matter covered herein and no other writings, verbal agreements and understandings are in effect. This Agreement may only be modified, changed or amended by another instrument in writing agreed to and signed by both parties to this Agreement.